Protein molecules are long and complex strings of amino acids that fold into compact shape to organise and catalyse metabolic and growth activities of biological cells. Correct protein folding is, therefore, essential to maintain our human health. Conversely, misfolded and unfolded proteins are non-functional, or even toxic, the effect of which have been found cause of a broad range of illnesses, such as neurodegenerative diseases (like Alzheimer's and Parkinson's), cystic fibrosis, type II diabetes and certain forms of cancers.

To maintain human health and save lives, scientists have been working hard to explore biological mechanisms that lead to different forms of protein folding, as well as possible control processes and treatments which help to develop therapeutic strategies to combat those diseases. In this science seminar, we are honoured to have Professor Franz-Ulrich Hartl and Professor Kazutoshi Mori (2012 and 2014 Shaw Laureates in Life Science and Medicine) to share their research and knowledge regarding "Chaperones" (Helper proteins which guide proper protein folding) and "Unfolded Protein Response" (cellular signalling pathway which helps regulate protein production) respectively.  

Date: 15.11.2023 (Wednesday)

Time: 4:30pm – 6:30pm

Seminar 1

Chaperones of the Cell: Role in Protein Folding and Neurodegenerative Diseases

Speaker: Professor Franz-Ulrich Hartl (2012 Shaw Laureate in Life Science and Medicine)

Seminar 2

Protein quality control by the unfolded protein response

Speaker: Professor Kazutoshi Mori (2014 Shaw Laureate in Life Science and Medicine)

Jointly organised by the Hong Kong Science Museum and the Hong Kong Laureate Forum
Major Partner: The Shaw Prize Foundation
Principal Sponsor: Lee Shau Kee Foundation